In human being ANCA-associated cGN, the overexpression of Gremlin-1 correlated with tubulointerstitial fibrosis [39], suggesting that this factor can also be involved in tubulointerstitial fibrosis with this pathology - Current concepts in The identification and characterisation of Rho Kinase Inhibitors

In human being ANCA-associated cGN, the overexpression of Gremlin-1 correlated with tubulointerstitial fibrosis [39], suggesting that this factor can also be involved in tubulointerstitial fibrosis with this pathology. glomerulonephritis. In NTS-injected mice, the iBET JQ1 inhibited renal Gremlin-1 overexpression and diminished glomerular damage, repairing podocyte figures. Chromatin immunoprecipitation assay shown BRD4 enrichment of the gene … Continue reading In human being ANCA-associated cGN, the overexpression of Gremlin-1 correlated with tubulointerstitial fibrosis [39], suggesting that this factor can also be involved in tubulointerstitial fibrosis with this pathology